Emma is a junior at Walnut Hills High School. Emma participated in a research experience with Dr. Stoddard in summer 2019. Her work focused on evaluating novel compounds for histone deacteylase 2 (HDAC2) and understanding the molecular interactions that optimized binding to the HDAC2 receptor. HDAC2 is a target for colorectal cancer, thus compounds that Emma evaluated are being targeted as colorectal cancer treatment options. Emma plans to attend college after high school then continue on to medical school.
Kellen (Psychology '21) completed a summer research experience in the MIR Lab in summer 2019. Her work focused on design of novel hydroxamate acid inhibitor derivatives for histone deacetylase 2 (HDAC2). HDAC2 is a relevant drug target for Alzheimer's disease, thus HDAC2 inhibitors might provide some relief to individuals suffering from this condition. After Rhodes Kellen plans to attend medical school.
Colin was a Chemistry major who worked in the MIR lab spring 2017 to spring 2019. Colin’s work focused on developing novel therapeutic proteins for primary membranous nephropathy, development of a computational suite of programs to facilitate data processing, and a collaborative project between Dr. Stoddard’s lab and Dr. Fatima Rivas lab at St. Jude Children’s Research hospital. Part of Colin’s work was published in PROTEINS: Structure Function and Bioinformatics December 2018. Colin is currently a graduate student at Medical University of South Carolina.
Mounika was a Biology major and has worked in the MIR lab since fall 2017 to spring 2019. Mounika’s work focused on developing novel therapeutic proteins for the autoimmune disorder primary membranous nephropathy in addition to the characterization of one of the proteins targeted in this disorder. In 2018 part of Mounika’s work was published in the journal PROTEINS: Structure Function and Bioinformatics. Mounika plans to attend medical school after Rhodes.
Serena completed a summer research experience in Dr. Stoddard’s lab summer 2018. Serena’s work helped to define the specific residues which the immune system was targeting on the protein receptor thrombospondin type-1 containing domain 7A in the autoimmune disorder primary membranous nephropathy. This work was published in PROTEINS: Structure Function and Bioinformatics December 2018. Serena is currently attending the College of Veterinary Medicine at Tuskegee University in Alabama.
Riya is a Chemistry major who completed a summer research experience in Dr. Stoddard’s lab summer 2018. Riya’s work helped to categorize the specific residues on the thrombospondin type-1 containing domain 7A that are being targeted by antibodies in the disorder primary membranous nephropathy. This work was published in PROTEINS: Structure Function and Bioinformatics December 2018. Riya plans to attend medical school after graduation from Rhodes.
Candace Hayes (BMB ’19) participated in research in the MIR lab Spring 2018. Her work help to demonstrate the impact of mutations in proteins on immunogenicity in regards to the phospholipase A2 receptor protein. Candace has been accepted to medical school and will be start fall 2019.
Caylon is a senior in high school and participated in a research experience in summer 2017. His work on design and optimization of boron containing hydroxamate acid derivatives for cancer therapy was presented at the regional Southeastern Regional Meeting of the American Chemical Society in Charlotte NC November 2017.
Alireza (Bio ’18) and participated in research in from spring 2018 to May 2018. His work focused on design novel proteins which could stop the progression of autoimmune disorders. Al is currently a physician scribe and intends to apply to medical school.
Xavier (BMB ’17) was the first student in the MIR lab and participated in research from fall 2015 to spring 2017. Xavier’s work focused on investigation of novel hydroxamate acid derivatives for colorectal and neuroblastoma treatment. Xavier’s work lead to a publication in October 2018 in Molecular Informatics. Currently, Xavier is an emergency room scribe and is currently applying to medical school.